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Antigenic Specificity | SNAI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. |
Immunogen | Immunogen: Recombinant human Zinc finger protein SNAI1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10433 / sc-10432 / sc-28199 |
Other Names | [Zinc finger protein SNAI1; SNAI1; SNAH; Protein snail homolog 1; Protein sna], [SNAI1; SNAI1; SNA; SNAH; SNAIL; SLUGH2; SNAIL1; dJ710H13.1; SNAH; Protein sna] |
Gene, Accession # | [SNAI1], Gene ID: 6615, NCBI: NP_005976.2, UniProt: O95863 |
Catalog # | MBS1495868 |
Price | $160, $235 |
Order / More Info | SNAI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |