SNAI1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySNAI1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionInvolved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
ImmunogenImmunogen: Recombinant human Zinc finger protein SNAI1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10433 / sc-10432 / sc-28199
Other Names[Zinc finger protein SNAI1; SNAI1; SNAH; Protein snail homolog 1; Protein sna], [SNAI1; SNAI1; SNA; SNAH; SNAIL; SLUGH2; SNAIL1; dJ710H13.1; SNAH; Protein sna]
Gene, Accession #[SNAI1], Gene ID: 6615, NCBI: NP_005976.2, UniProt: O95863
Catalog #MBS1495868
Price$160, $235
Order / More InfoSNAI1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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