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Antigenic Specificity | ITGAV - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ITGAV |
Other Names | [integrin alpha-V isoform 2; Integrin alpha-V; integrin alpha-V; integrin subunit alpha V; Vitronectin receptor subunit alpha] |
Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: NP_001138471.1, UniProt: P06756 |
Catalog # | MBS3221724 |
Price | $335 |
Order / More Info | ITGAV - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |