Phospho-ACK1 (Y826) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-ACK1 (Y826)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsDot Blot (DB), ELISA (EIA)
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DescriptionThis ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y826 of human ACK1. ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
Immunogenn/a
Other Names[Activated CDC42 kinase 1; ACK-1; Tyrosine kinase non-receptor protein 2; TNK2; ACK1]
Gene, Accession #[TNK2], Gene ID: 10188, NCBI: NP_001010938.1, UniProt: Q07912
Catalog #MBS9211014
Price$165, $370
Order / More InfoPhospho-ACK1 (Y826) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGuo A, et al. (2008) A 105, 692-7 Rikova K, et al. (2007) Cell 131, 1190-203 Huang PH, et al. (2007) Proc Natl Acad Sci U S A 104, 12867-72 Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM (2007) Proc Natl Acad Sci U S A 104, 5860-5 Goss VL, et al. (2006) Blood 107, 4888-97 Wolf-Yadlin A, et al. (2006) Mol Syst Biol 2, 54 Rush J, et al. (2005) Nat Biotechnol 23, 94-101
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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