Human Mitogen-Activated Protein Kinase 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Mitogen-Activated Protein Kinase 1
Clone[PAT1A4AT]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2b k
FormatProtein G purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionIntroduction: Mitogen-activated protein kinase 1 (MAPK1) is also known as extracellular signal-regulated kinase 2 (ERK2). Two similar (85% sequence identity) protein kinases were originally called ERK1 and ERK2. They were found during a search for protein kinases that are rapidly phosphorylated after activation of cell surface tyrosine kinasessuch as the epidermal growth factor receptor. Phosphorylation of ERKs leads to the activation of their kinase activity. The molecular events linking cell surface receptors to activation of ERKs are complex. It was found that RasGTP-binding proteins are involved in the activation of ERKs. Another protein kinase, Raf-1, was shown to phosphorylate a MAPK kinase, thus qualifying as a MAPK kinase kinas
ImmunogenImmunogen: Anti-human MAPK1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAPK1 amino acids 1-360 purified from E Coli.
Other Names[MAPK1; Mitogen-Activated Protein Kinase 1, Mouse Human; Mitogen-activated protein kinase 1; EC 2.7.11.24; Extracellular signal-regulated kinase 2; ERK-2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; p42-MAPK; ERT1; ERK; p38; p40; p41; ERK2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk], [MAPK1; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK2; PRKM1; PRKM2; MAP kinase 1; MAPK 1; ERK-2; p42-MAPK; MAP kinase 2; MAPK 2]
Gene, Accession #[MAPK1], Gene ID: 5594, NCBI: NP_002736.3
Catalog #MBS140363
Price$140, $205, $505
Order / More InfoHuman Mitogen-Activated Protein Kinase 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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