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Antigenic Specificity | Semaphorin-3A (C-terminal) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A/Fc chimera. One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchoredextracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A(Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade theinjured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons thatregenerate up to the injured |
Immunogen | Immunogen: Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the C-terminal region of human Sema3A. The sequence used has two amino acid differences from rat and mouse Sema3A, and has low homology to other semaphorin family members. |
Other Names | [Sema3A; Semaphorin III], [SEMA3A; SEMA3A; SemD; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; MGC133243; SEMAD] |
Gene, Accession # | Gene ID: 10371, NCBI: NP_006071.1, UniProt: Q14563 |
Catalog # | MBS472058 |
Price | $385 |
Order / More Info | Semaphorin-3A (C-terminal) Antibody from MYBIOSOURCE INC. |
Product Specific References | • Kolodokin, A.L. et al. (1993) Cell 75:1389.• Luo, Y. et al. (1993) Cell 75:217.• Pasterkamp, R.J. & Verhaagen, J. (2001) Brain Res Rev 35:36. |