Semaphorin-3A (C-terminal) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySemaphorin-3A (C-terminal)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionThe antibody detects a 95kDa* protein corresponding to the apparent molecular mass of Sema3A on SDS-PAGE immunoblots of human recombinant Sema3A/Fc chimera. One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI-anchoredextracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A(Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade theinjured spinal cord and surround the glial scar. In addition, the Sema3A co-receptors, Neuropilin-1 and Plexin-A1, are expressed on axons thatregenerate up to the injured
ImmunogenImmunogen: Semaphorin 3A synthetic peptide (coupled to carrier protein) corresponding to amino acids in the C-terminal region of human Sema3A. The sequence used has two amino acid differences from rat and mouse Sema3A, and has low homology to other semaphorin family members.
Other Names[Sema3A; Semaphorin III], [SEMA3A; SEMA3A; SemD; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; MGC133243; SEMAD]
Gene, Accession #Gene ID: 10371, NCBI: NP_006071.1, UniProt: Q14563
Catalog #MBS472058
Price$385
Order / More InfoSemaphorin-3A (C-terminal) Antibody from MYBIOSOURCE INC.
Product Specific References• Kolodokin, A.L. et al. (1993) Cell 75:1389.• Luo, Y. et al. (1993) Cell 75:217.• Pasterkamp, R.J. & Verhaagen, J. (2001) Brain Res Rev 35:36.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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