LRP6 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LRP6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~180 kDa of human LRP6 protein. It also reacts with mouse and rat. The other species are not tested. Low-desnsity lipoprotein receptor (LDLR)-related protein 6 (LRP6) is a member of the LDLR family which consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LRP5 cuases several human diseases including bone mineral density variability1, endosteal hyperostosis, autosomal dominant osteopetrosis type I etc. The V171 mutation in LRP5 causes high bone density by impairing the action of a normal antagonist of the Wnt pathway and thus increasing Wnt signaling. The activity of LRP5 and LRP6 can be inhibited by binding of some members of Dickkopf (DKK) family proteins. Upon stimulati |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the epitope KGTYF of human LRP6 protein |
| Other Names | [Rabbit LRP6; Low-density lipoprotein Receptor-related Protein 6 (LRP6)], [LRP6; LRP6; ADCAD2; FLJ90062; FLJ90421] |
| Gene, Accession # | [LRP6 (Non-phospho)], Gene ID: 4040, NCBI: NP_002327.2, UniProt: O75581 |
| Catalog # | MBS462069 |
| Price | $285 |
| Order / More Info | LRP6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zahid Khan et al. (2007), Molecular and Cellular Biology, 27 (20), 7291-7301. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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