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Antigenic Specificity | CD11b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Integrin alpha-M(ITGAM) detection. Tested with WB in Human, Mouse, Rat. Background: ITGAM(Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT(MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3(CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated(LFA) antigen type 1(ITGAL), and p150, 95(ITGAX). By in situ hybridization, Corbi et al.(1988) demonstrated that the genes encoding the alpha subunits of LFA1(ITGAL), Mac1, and p150, 95(ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et a |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD11b (177-192aa MEQLKKSKTLFSLMQY), different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids. |
Other Names | [Integrin alpha-M; integrin, alpha M(complement component 3 receptor 3 subunit); Antigen CD11b p170; CD11 antigen like family member B; CD11 antigen-like family member B; CD11b; CD11b antigen; CD11b/CD18; CD49d; Cell surface glycoprotein MAC 1 alpha subunit; Cell surface glycoprotein MAC-1 subunit alpha; Cell Surface Glycoprotein MAC1 Alpha Subunit; Complement component 3 receptor 3 subunit; Complement Component Receptor 3 Alpha; Complement receptor type 3, alpha subunit; CR 3 alpha chain; CR-3 alpha chain; CR3 Alpha Chain; CR3; CR3A; F730045J24Rik; Integrin Alpha M; Integrin alpha M chain; Integrin alpha M complement component 3 receptor 3 subunit; Integrin alpha-M; Integrin beta 2 alpha subunit; ITAM_HUMAN; ITGAM; Leukocyte Adhesion Receptor MO1; Ly-40; MAC 1; Mac-1a; MAC1; Mac1, alpha subunit; MAC1A; Macrophage antigen alpha polypeptide; MGC117044; Mo1, alpha subunit; MO1A; Neutrophil adherence receptor alpha M subunit; Neutrophil Adherence Receptor; SLEB6], [ITGAM; ITGAM; CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; CD11B; CR3A] |
Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: P11215.2, UniProt: P11215 |
Catalog # | MBS176783 |
Price | $280 |
Order / More Info | CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |