Prostate Apoptosis Response Protein-4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Prostate Apoptosis Response Protein-4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total prostate apoptosis response protein-4 protein. Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage acti |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human prostate apoptosis response protein-4. |
| Other Names | [PAR4; PRKC apoptosis WT1 regulator protein; PRKC; apoptosis; WT1] |
| Gene, Accession # | Gene ID: 5074, NCBI: NP_002574.2, UniProt: Q96IZ0 |
| Catalog # | MBS9400992 |
| Price | $200, $255 |
| Order / More Info | Prostate Apoptosis Response Protein-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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