ILK Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ILK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Integrin-linked kinase (ILK) is an adaptor and signaling protein that couples integrins to the actin cytoskeleton and coordinates signal transduction from extracellular matrix and growth factors. By interacting with the focal adhesion proteins PINCH, paxillin, and parvin, ILK regulates integrin-mediated cell adhesion and cytoskeletal dynamics within focal adhesions to regulate cell adhesion, spreading, and migration. ILK is involved in the suppression of apoptosis and promotion of cell survival through the phosphorylation of AKT (Ser473), GSK-3 (Ser9), myosin light chain (Ser18/19), and affixin. ILK activity is stimulated by PI3 kinase and negatively regulated by the tumor suppressor PTEN. |
| Immunogen | Immunogen: ILK antibody was raised in Rabbit using a recombinant human protein purified from E Coli as the immunogen |
| Other Names | [Rabbit ILK; ILK; ILK; ILK; integrin-linked kinase; 59 kDa serine/threonine-protein kinase; beta-integrin-linked kinase; BOS_14637; CG10504-PA; CG10504-PB; CT29478; Dmel_CG10504; DmILK; EGK_06531; ESTM24; ILK-1; ILK-2; Ilk-PA; Ilk-PB; integrin binding protein kinase; integrin linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; integrin-linked protein kinase-like protein; lost-contact; main squeeze; msq; p59; p59ILK; PANDA_014448; zilk] |
| Gene, Accession # | [ILK], Gene ID: 3611, NCBI: CAG28601.1, UniProt: Q13418 |
| Catalog # | MBS5310060 |
| Price | $375 |
| Order / More Info | ILK Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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