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Antigenic Specificity | Caveolin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Caveolin-1 protein. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.Wei Zhang, J. Biol. Chem., Jun 2000; 275: 20717.Rosalia Mora, J. Biol. Chem., Sep 1999; 274: 25708.Isabella Parolini, J. Biol. Chem., Sep 1999; 274: 25718.Phuong U. Le, J. Biol. Chem., Jan |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human Caveolin-1. |
Other Names | [CAV; CAV1; MSTP085; VIP21; caveolae protein] |
Gene, Accession # | Gene ID: 857, NCBI: NP_001744.2, UniProt: Q03135 |
Catalog # | MBS9409249 |
Price | $200, $255 |
Order / More Info | Caveolin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |