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Antigenic Specificity | CD8 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/ suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck. |
Immunogen | Immunogen: Ni-NTA purified recombinant human CD8 expressed in E Coli strain BL21 (DE3). |
Other Names | [CD8, partial; CD8; T-cell surface glycoprotein CD8 alpha chain; CD8a molecule; CD8], [CD8A; CD8] |
Gene, Accession # | [CD8], Gene ID: 403158, NCBI: ABA55041.1 |
Catalog # | MBS418376 |
Price | $445 |
Order / More Info | CD8 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Veillette, A. et al. 1988. Cell 55:301 |