Human Cytoplasmic protein NCK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Cytoplasmic protein NCK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors. |
| Immunogen | Immunogen: Recombinant human Cytoplasmic protein NCK1 protein(58-377aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22442 / sc-290 / sc-50365 |
| Other Names | [NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alpha; NCK1; NCK], [NCK1; NCK1; NCK; nck-1; NCKalpha; NCK; Nck-1] |
| Gene, Accession # | [NCK1], Gene ID: 4690, NCBI: NP_001177725.1, UniProt: P16333 |
| Catalog # | MBS1492286 |
| Price | $120, $160 |
| Order / More Info | Human Cytoplasmic protein NCK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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