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Antigenic Specificity | TAB3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TAB3 protein. The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the N terminal of human TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
Other Names | [NAP1; MAP3K7IP3] |
Gene, Accession # | [TAB3], Gene ID: 257397, NCBI: NP_690000.3, UniProt: Q8N5C8 |
Catalog # | MBS9408550 |
Price | $255 |
Order / More Info | TAB3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |