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Antigenic Specificity | ITGB3BP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ITGB3BP protein. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Full length fusion protein |
Other Names | [integrin beta 3 binding protein (beta3-endonexin), CENPR, NRIF3, TAP20, CENP-R, HSU37139] |
Gene, Accession # | [ITGB3BP], Gene ID: 23421, NCBI: BC014385 |
Catalog # | MBS9403946 |
Price | $200, $255 |
Order / More Info | ITGB3BP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |