CD200R3, Mouse Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD200R3, Mouse
CloneBa91
Host SpeciesMouse
Reactive Speciesmouse
IsotypeIgG2a
Formatunconjugated
Size1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Functional Studies (FS), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThe monoclonal antibody Ba91 recognizes mouse CD200 Receptor-like 3 (CD200R3), a protein of ~38 kDa or ~74 kDa (reduced or non-reduced condition, respectively). CD200R3 presumably exists as a disulfide-linked dimer on the cell surface. The OX-2, or CD200 receptor (CD200R), belongs to the immunoglobulin superfamily. CD200R contains two Ig-like extracellular domains and mediates inhibitory signals in myeloid cells. Mice deficient for the ligand CD200 develop enhanced experimental allergic encephalomyelitis and collagen-induced arthritis. Unlike CD200R, the CD200R-like receptors functions as activating receptors. They contain short cytoplasmic tails and a lysine residue in the transmembrane region and are likely to signal via adaptor proteins
ImmunogenImmunogen: Mouse primary basophils
Other Names[CD200R3; CD200RLb; OX-2 Receptor 3], [Cd200r3; Cd200r3; AI505817; BB106877; mCD200RLb; 4733401I18Rik; 4833409J19Rik; Cd200rlb; CD200 receptor-like 3; CD200RLb]
Gene, Accession #[CD200R3], Gene ID: 74603, NCBI: NP_001121605.1
Catalog #MBS584709
Price$2545
Order / More InfoCD200R3, Mouse Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKojima, T et al; Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner. J Immunol 2007, 179: 7093
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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