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Antigenic Specificity | CD200R3, Mouse |
Clone | Ba91 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Functional Studies (FS), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody Ba91 recognizes mouse CD200 Receptor-like 3 (CD200R3), a protein of ~38 kDa or ~74 kDa (reduced or non-reduced condition, respectively). CD200R3 presumably exists as a disulfide-linked dimer on the cell surface. The OX-2, or CD200 receptor (CD200R), belongs to the immunoglobulin superfamily. CD200R contains two Ig-like extracellular domains and mediates inhibitory signals in myeloid cells. Mice deficient for the ligand CD200 develop enhanced experimental allergic encephalomyelitis and collagen-induced arthritis. Unlike CD200R, the CD200R-like receptors functions as activating receptors. They contain short cytoplasmic tails and a lysine residue in the transmembrane region and are likely to signal via adaptor proteins |
Immunogen | Immunogen: Mouse primary basophils |
Other Names | [CD200R3; CD200RLb; OX-2 Receptor 3], [Cd200r3; Cd200r3; AI505817; BB106877; mCD200RLb; 4733401I18Rik; 4833409J19Rik; Cd200rlb; CD200 receptor-like 3; CD200RLb] |
Gene, Accession # | [CD200R3], Gene ID: 74603, NCBI: NP_001121605.1 |
Catalog # | MBS584709 |
Price | $2545 |
Order / More Info | CD200R3, Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | Kojima, T et al; Mast cells and basophils are selectively activated in vitro and in vivo through CD200R3 in an IgE-independent manner. J Immunol 2007, 179: 7093 |