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Antigenic Specificity | Langerin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 3mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
Immunogen | Immunogen: Recombinant human C-type lectin domain family 4 member K protein Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [C type lectin domain family 4 member K; CD207; CD207 antigen; langerin; CLEC4K; Langerhans cell specific c type lectin; Langerin] |
Gene, Accession # | Gene ID: 50489, UniProt: Q9UJ71 |
Catalog # | MBS2541739 |
Price | $110, $150, $225 |
Order / More Info | Langerin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |