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Antigenic Specificity | Neurocan Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican/chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.Protein Function: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N- |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human Neurocan (HENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA). Subcellular Localization: Secreted. Tissue Specificity: Brain. |
Other Names | [Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3; NEUR] |
Gene, Accession # | [NCAN], Gene ID: 1463, NCBI: NP_004377.2, UniProt: O14594 |
Catalog # | MBS1750914 |
Price | $315 |
Order / More Info | Neurocan Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |