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Antigenic Specificity | Phospho-Paxillin(Ser178) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Paxillin(Ser178) antibody detects endogenous levels of Paxillin only when phosphorylated at Sersine 178. Description: PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. The SH2 domain of Crk binds to tyrosine phosphorylated paxillin. Three alternatively-spliced isoforms have been described.Function: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).Subunit Structure: Binds in vi |
Immunogen | Immunogen: A synthesized peptide derived from human Paxillin around the phosphorylation site of Sersine 178 Subcellular Location: Cytoplasm > Cytoskeleton. Cell Junction > Focal Adhesion. |
Other Names | [FLJ16691; FLJ23042; Paired box protein Pax 1; PAX 1; PAX1; PAXI_HUMAN; Paxillin alpha; Paxillin; PXN; PXN protein] |
Gene, Accession # | [PXN], Gene ID: 5829, NCBI: NP_001074324.1, UniProt: P49023 |
Catalog # | MBS9600023 |
Price | $240, $280 |
Order / More Info | Phospho-Paxillin(Ser178) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |