Phospho-Paxillin(Ser178) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Paxillin(Ser178)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phospho-Paxillin(Ser178) antibody detects endogenous levels of Paxillin only when phosphorylated at Sersine 178. Description: PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions. The SH2 domain of Crk binds to tyrosine phosphorylated paxillin. Three alternatively-spliced isoforms have been described.Function: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).Subunit Structure: Binds in vi
ImmunogenImmunogen: A synthesized peptide derived from human Paxillin around the phosphorylation site of Sersine 178 Subcellular Location: Cytoplasm > Cytoskeleton. Cell Junction > Focal Adhesion.
Other Names[FLJ16691; FLJ23042; Paired box protein Pax 1; PAX 1; PAX1; PAXI_HUMAN; Paxillin alpha; Paxillin; PXN; PXN protein]
Gene, Accession #[PXN], Gene ID: 5829, NCBI: NP_001074324.1, UniProt: P49023
Catalog #MBS9600023
Price$240, $280
Order / More InfoPhospho-Paxillin(Ser178) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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