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Antigenic Specificity | CDH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of U251 cell line, using CDH2 antibody. Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development (1). The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells. The cytoplasmic domain of classical cadherins interacts with 2-catenin, 3-catenin (also called plakoglobin), and p120 catenin. 2-catenin and 3-catenin associate with +/--catenin, |
Immunogen | Immunogen: A synthetic peptide of human CDH2 |
Other Names | [cadherin-2 isoform 2; Cadherin-2; cadherin-2; cadherin 2; CDw325; Neural cadherin; N-cadherin; CD_antigen: CD325] |
Gene, Accession # | [CDH2], Gene ID: 1000, NCBI: NP_001295105.1, UniProt: P19022 |
Catalog # | MBS4150227 |
Price | $385 |
Order / More Info | CDH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |