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Antigenic Specificity | Phospho-MAPKAPK-2 (Thr221/222) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MAPKAPK-2 (Thr221/222) Antibody detects endogenous levels of MAPKAPK-2 only when phosphorylated at Thr221/222. Description: Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X2-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, CEP131, ELAVL1, HNRNPA0, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1, PABPC1, PARN, PDE4A, RCSD1, RPS |
Immunogen | Immunogen: A synthesized peptide derived from human MAPKAPK-2 around the phosphorylation site of Thr221/222. Tissue Specificity: Expressed in all tissues examined. |
Other Names | [MAP kinase activated protein Kinase 2; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPK2_HUMAN; MAPKAP K2; MAPKAP kinase 2; MAPKAPK 2; MAPKAPK-2; MAPKAPK2; Mitogen activated protein kinase activated protein kinase 2; MK 2; MK2] |
Gene, Accession # | [MAPKAPK-2], Gene ID: 9261, NCBI: NP_004750.1, UniProt: P49137 |
Catalog # | MBS9610671 |
Price | $225, $280, $340 |
Order / More Info | Phospho-MAPKAPK-2 (Thr221/222) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |