Edit |   |
---|---|
Antigenic Specificity | CXCR3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CXCR3 antibody is human, mouse and rat reactive. At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms. The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2). Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker |
Immunogen | Immunogen: CXCR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3. Buffer: CXCR3 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [CXCR3; GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; GPR9; C-X-C chemokine receptor type 3; CXC-R3; chemokine (C-X-C motif) receptor 3], [CXCR3; CXCR3; GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R; GPR9; CXC-R3; CXCR-3; IP-10 receptor] |
Gene, Accession # | [CXCR3], Gene ID: 2833, NCBI: NP_001136269, UniProt: P49682 |
Catalog # | MBS153408 |
Price | $375 |
Order / More Info | CXCR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |