TOX Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TOX |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No alternatively spliced transcript variants have been observed. TOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells. |
| Immunogen | Immunogen: TOX antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TOX. Buffer: TOX Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TOX; TOX1; KIAA0808; Thymocyte selection-associated high mobility group box protein TOX; Thymus high mobility group box protein TOX; thymocyte selection-associated high mobility group box protein TOX], [TOX; TOX; TOX1; KIAA0808] |
| Gene, Accession # | [TOX], Gene ID: 9760, NCBI: NP_055544, UniProt: O94900 |
| Catalog # | MBS151222 |
| Price | $375 |
| Order / More Info | TOX Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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