CD95 / FAS / TNFRSF6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD95 / FAS / TNFRSF6 |
| Clone | [B-R18] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, o |
| Immunogen | Immunogen: Recombinant human CD95 protein |
| Other Names | [ALPS1A, Apoptosis APO1 antigen 1, Apoptosis-mediating surface antigen FAS, APT1, Delta Fas/APO1/CD95, Fas (TNF receptor superfamily, member 6), Fas AMA, Fas cell surface death receptor, FAS1, FASL receptor, FASLG receptor, FASTM, Surface antigen APO1, TNF receptor superfamily member 6 (TNFR6), Tumor necrosis factor receptor superfamily member 6 (TNFRSF6)], [FAS; FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; APT1; FAS1; TNFRSF6] |
| Gene, Accession # | [FAS], Gene ID: 355, NCBI: NP_000034.1, UniProt: P25445 |
| Catalog # | MBS438571 |
| Price | $190, $340, $340 |
| Order / More Info | CD95 / FAS / TNFRSF6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sasaki et al. Br J Urol 81: 852, 1998. Sugihara et al. Anticancer Res 17: 3861, 1997. Kondo et al. J Pathol 183: 75, 1997 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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