CBFA2T3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCBFA2T3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, sheep, chicken
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: CBFA2T3 Antibody detects endogenous levels of CBFA2T3. Description: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Reduces the protein levels and stability of the transcriptinal regulator HIF1A; interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway (PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of gly
ImmunogenImmunogen: A synthesized peptide derived from human CBFA2T3. Tissue Specificity: Widely expressed with higher expression in heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. Expressed in hematopoietic cells (at protein level).
Other Names[Cbfa2t3; Ccore binding factor runt domain alpha subunit 2 translocated to 3; ETO2; hMTG16; hMTG16a; hMTG16b; MTG16; MTG16_HUMAN; MTG8 related gene 2; MTG8 related protein MTG16a; MTG8 related protein MTG16b; MTG8-related protein 2; MTGR2; Myeloid translocation gene 8 and 16b; Myeloid translocation gene on chromosome 16 protein; Protein CBFA2T3; Zinc finger MYND domain-containing protein 4; ZMYND4]
Gene, Accession #[CBFA2T3], Gene ID: 863, NCBI: NP_005178.4, UniProt: O75081
Catalog #MBS9611327
Price$240, $280
Order / More InfoCBFA2T3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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