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Antigenic Specificity | Vinculin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Vinculin is a membrane-cytoskeletal protein in humans that is encoded by the VCL gene. Vinculin is associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Vinculin's ability to interact with integrins appears to be critical for control of cytoskeletal mechanics, cell spreading, and lamellipodia formation. Thus, vinculin appears to play a key role in shape control based on its ability to modulate focal adhesion structure and function. |
Immunogen | Source Note: This polyclonal antibody is produced by immunizing animals with a polypeptide corresponding to Vinculin protein. |
Other Names | [vinculin isoform VCL; Vinculin; vinculin; vinculin; Metavinculin; MV], [Metavinculin; MV] |
Gene, Accession # | [VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
Catalog # | MBS435236 |
Price | $280, $400 |
Order / More Info | Vinculin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |