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Antigenic Specificity | PLCG2 |
Clone | [4F1E8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
Immunogen | Immunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2(cERDINSLpYDVSRMYV)). |
Other Names | [FCAS3; APLAID; PLC-IV; PLC-gamma-2] |
Gene, Accession # | [PLCG2], Gene ID: 5336, NCBI: NP_002652.2, UniProt: P16885 |
Catalog # | MBS8539400 |
Price | $280 |
Order / More Info | PLCG2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |