NOX3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | NOX3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins. The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4). |
| Immunogen | Immunogen: NOX3 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX3. Buffer: NOX3 antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [NAPDH oxidase 3; NOX-3; GP91-3; MOX2; MOX-2; NADPH oxidase 3], [NOX3; NOX3; MOX-2; GP91-3; MOX2; MOX-2; GP91-3] |
| Gene, Accession # | [NOX3], Gene ID: 50508, NCBI: NP_056533 |
| Catalog # | MBS153341 |
| Price | $375 |
| Order / More Info | NOX3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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