CDK2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CDK2 |
| Clone | [1534CT665.36.16] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CDK2 antibody is generated from a mouse immunized with protein from human CDK2. Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in o |
| Immunogen | n/a |
| Other Names | [Purified Mouse (Mab); Cyclin-dependent kinase 2; Cell division protein kinase 2; p33 protein kinase; CDK2; CDKN2] |
| Gene, Accession # | [CDK2], Gene ID: 1017, NCBI: NP_001277159.1, UniProt: P24941 |
| Catalog # | MBS9215498 |
| Price | $165, $370 |
| Order / More Info | CDK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Elledge S.J.,et al.EMBO J. 10:2653-2659(1991).Tsai L.-H.,et al.Nature 353:174-177(1991).Ninomiya-Tsuji J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:9006-9010(1991).Nishikawa T.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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