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Antigenic Specificity | SPDYA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 ge |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [MGC110856; MGC57218; Ringo3; SPDY1; SPY1], [SPDYA; SPDYA; SPY1; SPDY1; RINGO3; RINGOA; RINGO A; hSpy/Ringo A; Spy1] |
Gene, Accession # | [SPDYA], Gene ID: 245711, NCBI: Q5MJ70.2, UniProt: Q5MJ70 |
Catalog # | MBS126557 |
Price | $200, $275, $430 |
Order / More Info | SPDYA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |