ARPP19 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityARPP19
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: ARPP19 antibody detects endogenous levels of total ARPP19. Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.Subunit Structure: Interacts (when phosphorylated at Ser-62) with PPP2R2D (By similarity). Interacts with SNCA.Post-translational Modifications: Phosphorylation at Ser-62 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and subsequent inactivation of PP2A (
ImmunogenImmunogen: A synthesized peptide derived from human ARPP19 Subcellular Location: Cytoplasm. Tissue Specificity: Expression may be regulated by miR-451. Similarity: Belongs to the endo sulfine family. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (91%)
Other Names[ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19]
Gene, Accession #[ARPP19], Gene ID: 10776, NCBI: NP_001293120.1, UniProt: P56211
Catalog #MBS9609642
Price$240, $280
Order / More InfoARPP19 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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