ZBP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZBP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionZBP1 Antibody: Z-DNA binding protein 1 (ZBP1) belongs to a family of proteins that contain the Zalpha domain which binds specifically to left-handed Z-DNA and Z-RNA. ZBP1 was initially identified as a novel gene that was up-regulated in activated macrophages in mice bearing ascites tumors, suggesting that is may play a role in processes such as host response in neoplasia. More recent reports indicate that the cytosolic ZBP1 has can act like the toll-like receptor TLR9 by detecting cytosolic double-stranded (ds) DNA and trigger induction of type I interferon and other innate immune responses. It is thought that the binding of ZBP1 to dsDNA enhances its association with innate immune response proteins such as the IRF3 transcription factor and
ImmunogenImmunogen: ZBP1 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human ZBP1. Buffer: ZBP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[ZBP1; DAI; DLM1; DLM-1; C20orf183; Z-DNA-binding protein 1; Tumor stroma and activated macrophage protein DLM-1; Z-DNA binding protein 1], [ZBP1; ZBP1; DAI; DLM1; DLM-1; C20orf183; C20orf183; DLM1]
Gene, Accession #[ZBP1], Gene ID: 81030, NCBI: EAW75510, UniProt: Q9H171
Catalog #MBS150830
Price$375
Order / More InfoZBP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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