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Antigenic Specificity | Human Cytochrome C |
Clone | [15F10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | DyLight 488 conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome. |
Immunogen | Immunogen: E Coli-derived human Cytochrome C recombinant protein (Position: G2-E105). Human Cytochrome C shares 91% amino acid (aa) sequence identity with both mouse and rat Cytochrome C. |
Other Names | [Mouse IgG Human Cytochrome C DyLight 488 Conjugated, Flow Validated; Cytochrome c; CYCS; CYC; Cytochrome c, somatic] |
Gene, Accession # | [CYCS], Gene ID: 54205, NCBI: NP_061820.1, UniProt: P99999 |
Catalog # | MBS1752283 |
Price | $330 |
Order / More Info | Human Cytochrome C Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Garcia-Heredia JM, et al. Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. FEBS Lett, 2012 Jan 20. 2. Rajagopal BS, et al. The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochem J, 2013 Dec 15. 3. Simon M, et al. Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence. J Biol Inorg Chem, 2013 Jan. |