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Antigenic Specificity | CD105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Endoglin(ENG) detection. Tested with WB, IHC-P in Human. Background: Endoglin(Osler-Rendu-Weber syndrome 1), CD105, is a type I membrane glycoprotein located on cell surfaces and is a part of the TGF beta receptor complex. Its gene is mapped to human chromosome 8. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts and smooth muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling and has been found to be elevated in pregnant women who subsequently develop preeclampsia. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD105 (26-44aa ETVHCDLQPVGPERGEVTY). |
Other Names | [Endoglin; endoglin; CD 105; CD105; CD105 antigen; EGLN_HUMAN; END; Endoglin; ENG; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; SN6], [ENG; ENG; END; HHT1; ORW1; END] |
Gene, Accession # | [ENG], Gene ID: 2022, NCBI: P17813.2, UniProt: P17813 |
Catalog # | MBS175174 |
Price | $315 |
Order / More Info | CD105 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |