PIP5K1A (N-term), 19-50 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PIP5K1A (N-term), 19-50 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PIP5K1A (N-term), 19-50 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PIP5K1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-50 amino acids from the N-terminal region of human PIP5K1A. Overexpression of phosphatidylinositol phosphate 5-kinase alpha (PIP5KIalpha), which synthesizes PIP2, suppresses apoptosis, whereas a kinase-deficient mutant does not. Protection by the wild-type PIP5KIalpha isaccompanied by decreases in the generation of activated caspases and of caspase 3-cleaved PARP. Protection is not mediated through PIP3 or Akt activation. An anti-apoptotic role for PIP(2) is substantiated by the finding that PIP5KIalpha is cleaved by caspase 3 during apoptosis, and cleavage inactivates PIP5KIalpha in vitro. Mutation of the P(4) position (D279A) of th |
| Immunogen | n/a |
| Other Names | [Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; PIP5K1-alpha; PtdIns(4)P-5-kinase 1 alpha; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha; PIP5K1A] |
| Gene, Accession # | [PIP5K1A], Gene ID: 8394, NCBI: NP_001129108.1, UniProt: Q99755 |
| Catalog # | MBS9213963 |
| Price | $165, $370 |
| Order / More Info | PIP5K1A (N-term), 19-50 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Doughman, R.L., et al., J. Biol. Chem. 278(25):23036-23045 (2003). Loijens, J.C., et al., J. Biol. Chem. 271(51):32937-32943 (1996). Xie, Y., et al., Cytogenet. Cell Genet. 88 (3-4), 197-199 (2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies