PSEN2 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPSEN2 (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
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DescriptionThis PSEN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-65 amino acids from the N-terminal region of human PSEN2(Presenilin-2 NTF subunit). Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Immunogenn/a
Other Names[Presenilin-2; PS-2; 3423-; AD3LP; AD5; E5-1; STM-2; Presenilin-2 NTF subunit; Presenilin-2 CTF subunit; PSEN2; AD4; PS2; PSNL2; STM2]
Gene, Accession #[PSEN2], Gene ID: 5664, NCBI: NP_000438.2, UniProt: P49810
Catalog #MBS9211943
Price$165, $370
Order / More InfoPSEN2 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLevy-Lahad E.,et al.Science 269:973-977(1995). Rogaev E.I.,et al.Nature 376:775-778(1995). Li J.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:12180-12184(1995). Levy-Lahad E.,et al.Genomics 34:198-204(1996). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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