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Antigenic Specificity | ROCK1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ROCK1 Antibody detects endogenous levels of total ROCK1. ROCK1 Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. |
Immunogen | Immunogen: A synthesized peptide derived from human ROCK1 |
Other Names | [MGC131603; MGC43611; p160 ROCK-1; p160-ROCK; p160ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho kinase; Rho-associated protein kinase 1; Rho-associated; coiled-coil containing protein kinase 1; Rho-associated; coiled-coil-containing protein kinase] |
Gene, Accession # | [ROCK1], Gene ID: 6093, NCBI: NP_005397.1, UniProt: Q13464 |
Catalog # | MBS8512515 |
Price | $290 |
Order / More Info | ROCK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |