Edit |   |
---|---|
Antigenic Specificity | GSK3a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glycogen synthase kinase 3 is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3alpha and Ser9 of GSK-3beta. GSK-3 has also been implicated in alzheimer's disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3. |
Immunogen | Immunogen: GSK3a antibody was raised in Rabbit using synthetic peptide from human GSK-3alpha as the immunogen. |
Other Names | [Rabbit GSK3a; GSK3a; GSK3a; GSK3a; GSKa 3; GSKa 3; Glycogen synthase kinase-3; GSK-3 alpha; GSK-3 alpha; GSKa-3; DKFZp686D0638; GSKa-3] |
Gene, Accession # | [GSK3a], Gene ID: 2931, UniProt: P49840 |
Catalog # | MBS5311337 |
Price | $475 |
Order / More Info | GSK3a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |