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Antigenic Specificity | Cullin 5 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Cullin-5 is a protein that in humans is encoded by the CUL5 gene. Cul5 inhibits cellular proliferation, potentially through its involvement in the SOCS/ BC-box/ eloBC/ cul5/ RING E3 ligase complex, which functions as part of the ubiquitin system for protein degradation. One study have shown that Cul5 plays a role in Reelin signaling cascade, participating in the DAB1 degradation and thus ensuring the negative feedback mechanism of Reelin signaling during corticogenesis.Protein Function: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contri |
Immunogen | Immunogen: E Coli-derived human Cullin 5 recombinant protein (Position: A2-D105). |
Other Names | [Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1; CUL5; VACM1] |
Gene, Accession # | [CUL5], Gene ID: 8065, NCBI: NP_003469.2, UniProt: Q93034 |
Catalog # | MBS1750730 |
Price | $280 |
Order / More Info | Cullin 5 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |