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Antigenic Specificity | KCNQ2/3/4/5 (Phospho Thr217/246/223/251) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-KCNQ2/3/4/5 (T217/246/223/251) Polyclonal Antibody detects endogenous levels of KCNQ2/3/4/5 protein only when phosphorylated at T217/246/223/251. The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At leas |
Immunogen | Immunogen: Synthesized peptide derived from human KCNQ2/3/4/5 around the phosphorylation site of T217/246/223/251 |
Other Names | [Rabbit KCNQ2/3/4/5 (phospho Thr217/246/223/251); KCNQ2; Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; KCNQ3; Potassium voltage-gated channel subfamily KQT me] |
Gene, Accession # | [KCNQ2/3/4/5], Gene ID: 3785, NCBI: O43526.2, UniProt: O43526 |
Catalog # | MBS9705650 |
Price | $130, $220, $325 |
Order / More Info | KCNQ2/3/4/5 (Phospho Thr217/246/223/251) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |