BIK (N-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BIK (N-TERMINAL) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item detects an epitope within the N-terminal (NT) region of Bcl-2-interacting killer (Bik) also known as natural born killer (Nbk). Bik is a Bcl-2 homology domain 3 (BH3)-only protein of 18kD which requires the BAX gene for activation. Bik forms heterodimers with various antiapoptotic proteins such as Bcl-2 and Bcl-XL, inhibiting their antiapoptotic function. This can result in the release of Ca2+ and cytochrome C into the cytosol, leading to apoptosis. . . Loss of Bik is a common feature of clear-cell renal cell carcinoma (RCC), and is thought to act as a renal tissue-specific tumour suppressor gene. MBS221461 detects an epitope within the N-terminal (NT) region of Bcl-2-interacting killer (Bik) also known as natural born killer (N |
| Immunogen | Immunogen: 15 amino acid peptide from near the amino terminus of human Bik. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Bik were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
| Other Names | [bcl-2-interacting killer; Bcl-2-interacting killer; bcl-2-interacting killer; apoptosis inducer NBK; apoptosis-inducing NBK; BCL2-interacting killer (apoptosis-inducing); Apoptosis inducer NBK; BIP1; BP4], [BIK; BIK; BP4; NBK; BIP1; NBK] |
| Gene, Accession # | [BIK], Gene ID: 638, NCBI: NP_001188.1, UniProt: Q13323 |
| Catalog # | MBS221461 |
| Price | $375 |
| Order / More Info | BIK (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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