Edit |   |
Antigenic Specificity | Human ccbe1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for |
Immunogen | Immunogen: Recombinant human ccbe1 (Sf9). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant human ccbe1 (Tyr35-Pro406) derived from Sf9 insect cells. |
Other Names | [human ccbe1; Collagen and calcium-binding EGF domain-containing protein 1], [CCBE1; CCBE1; KIAA1983] |
Gene, Accession # | [ccbe1], Gene ID: 147372, NCBI: NP_597716.1, UniProt: Q6UXH8 |
Catalog # | MBS691084 |
Price | $280 |
Order / More Info | Human ccbe1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Karpanen T & Alitalo K, Annu Rev Pathol Dis 3, 2008 2. Oliver G & Alitalo K, Annu Rev Cell Dev Biol 21, 2005 3. Cueni LN & Detmar M, J Invest Dermatol 126, 2006 4. Fang J et al, Am J Hum Genet 67, 2000 5. Van Balkom ID et al, Am J Med Genet 112, 2002 6. Bellini C et al, Am J Med Genet. 120A, 2003 7. Hogan BM et al, Nat Genet 41, 2009 8. Maquat LE, Rev Mol Cell Biol 5, 2004 9. Yaniv K et al, Nat Med 12, 2006 10. Kuchler AM et al, Curr Biol 16, 2006 |