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Antigenic Specificity | ATF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATF7 antibody detects endogenous levels of total ATF7. Function: Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.Subunit Structure: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members. Interacts with JNK2; the interaction does not phosphorylate ATF7 but acts |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Nucleus > Nucleoplasm. Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery. Tissue Specificity: Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta. Predicted Cross Reactivity |
Other Names | [1110012F10Rik; 9430065F09Rik; Activating transcription factor 7; AI549878; ATF7; Atf7 protein; ATF7_HUMAN; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF 7; Cyclic AMP-dependent transcription factor ATF-7; MGC31554; MGC57182; Transcription factor ATF A; Transcription factor ATF-A] |
Gene, Accession # | [ATF7], Gene ID: 11016, NCBI: NP_001123532.1, UniProt: P17544 |
Catalog # | MBS9604568 |
Price | $240, $280 |
Order / More Info | ATF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |