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Antigenic Specificity | VEGFA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human VEGFA (NP 001165099.1). |
Other Names | [VPF; VEGF; MVCD1] |
Gene, Accession # | [VEGFA], Gene ID: 7422, NCBI: NP_001191313.1, UniProt: P15692 |
Catalog # | MBS8545739 |
Price | $280 |
Order / More Info | VEGFA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |