PDX1 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDX1 (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis PDX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-55 amino acids from the N-terminal region of human PDX1. Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic
Immunogenn/a
Other Names[Pancreas/duodenum homeobox protein 1; PDX-1; Glucose-sensitive factor; GSF; Insulin promoter factor 1; IPF-1; Insulin upstream factor 1; IUF-1; Islet/duodenum homeobox-1; IDX-1; Somatostatin-transactivating factor 1; STF-1; PDX1; IPF1; STF1]
Gene, Accession #[PDX1], Gene ID: 3651, NCBI: NP_000200.1, UniProt: P52945
Catalog #MBS9203180
Price$165, $370
Order / More InfoPDX1 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStoffel M.,et al.Genomics 28:125-126(1995). Inoue H.,et al.Diabetes 45:789-794(1996). Hiroshi I.,et al.Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases. Marshak S.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases. Hara M.,et al.Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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