Bcl-2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Bcl-2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Bcl-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, monkey |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human and monkey Bcl-2. Detects a band of ~25kDa by Western blot. Bcl-2 alpha and beta are alternatively spliced isoforms of 25 kDa and 22 kDa integral membrane proteins that typically inhibit apoptosis; however Bcl-2 can also be pro-apoptotic. Bcl-2 is found in the mitochondrial, ER and nuclear membranes, and its subcellular location appears to affect whether it is pro-apoptotic or anti-apoptotic. Bcl-2 becomes pro-apoptotic when it is either cleaved by caspase-3 or targeted to the mitochondrial membrane. When Bcl-2 is targeted to the ER membrane, it protects cells from apoptosis induced by Bax overexpression. ER membrane Bcl-2 may protect against apoptosis by preserving the integrity of the mitochondria after an apoptotic stimu |
| Immunogen | Immunogen: Synthetic peptide corresponding to a portion of human Bcl-2. |
| Other Names | [Bcl-2], [BCL2; BCL2; Bcl-2; PPP1R50] |
| Gene, Accession # | Gene ID: 596, NCBI: P10415.2, UniProt: P10415 |
| Catalog # | MBS565340 |
| Price | $345 |
| Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies