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Antigenic Specificity | HLA-DPB1 (Center), 77-105 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.45 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HLA-DPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the Central region of human HLA-DPB1. HLA-DPB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha(DPA) and a beta chain (DPB), both anchored in the membrane. Itplays a central role in the immune system by presenting peptidesderived from extracellular proteins. Class II molecules areexpressed in antigen presenting cells (APC: B lymphocytes,dendritic cells, macrophages). The beta chain is approximately26-28 kDa and its gene contains 6 exons. Exon one encodes theleader peptide, exons 2 and 3 encode the two extracellular dom |
Immunogen | n/a |
Other Names | [HLA class II histocompatibility antigen; DP beta 1 chain; HLA class II histocompatibility antigen; DP(W4) beta chain; MHC class II antigen DPB1; HLA-DPB1; HLA-DP1B] |
Gene, Accession # | [HLA-DPB1], Gene ID: 3115, NCBI: NP_002112.3, UniProt: P04440 |
Catalog # | MBS9211246 |
Price | $165, $370 |
Order / More Info | HLA-DPB1 (Center), 77-105 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Yang, J.H., et al. Tissue Antigens 76(4):282-288(2010) Wang, P., et al. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 24(6):261-263(2010) Ovsyannikova, I.G., et al. PLoS ONE 5 (7), E11806 (2010) : Mychaleckyj, J.C., et al. Clin Trials 7 (1 SUPPL), S75-S87 (2010) : |