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Antigenic Specificity | MAP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using MAP2 antibody. Microtubule-associated protein 2 (MAP2) is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics, and organelle trafficking in axons and dendrites (1). Multiple MAP2 isoforms are expressed in neurons, including high molecular weight MAP2A and MAP2B (280 and 270 kDa), and low molecular weight MAP2C and MAP2D (70 and 75 kDa). Phosphorylation of MAP2 modulates its association with the cytoskeleton and is developmentally regulated. GSK-3 and p44/42 MAP kinase phosphorylate MAP2 at Ser136, Thr1620, and Thr1623 (2, 3). Phosphorylation at Thr1620/1623 by GSK-3 inhibits MAP2 associa |
Immunogen | Immunogen: Recombinant protein of human MAP2 |
Other Names | [MAP2 protein, partial; Microtubule-associated protein 2; microtubule-associated protein 2; microtubule associated protein 2] |
Gene, Accession # | [MAP2], Gene ID: 4133, NCBI: AAH66648.1 |
Catalog # | MBS4150119 |
Price | $385 |
Order / More Info | MAP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |