Mouse CTLA-4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CTLA-4
Clone[6G10]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS), Neutr
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DescriptionCD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28.
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of CTLA-4.
Other Names[Ctla4; Cd152; Ly-56; Ctla-4], [Ctla4; Ctla4; Cd152; Ly-56; Ctla-4; Cd152; CTLA-4]
Gene, Accession #[CTLA-4], Gene ID: 12477, NCBI: NP_033973.2, UniProt: P09793
Catalog #MBS690911
Price$490
Order / More InfoMouse CTLA-4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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