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Antigenic Specificity | Human AKAP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). |
Immunogen | Immunogen: Recombinant human A-kinase anchor protein 10, mitochondrial protein (413-662aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109187 / sc-109188 / sc-109189 / sc-98755 |
Other Names | [AKAP-10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10; AKAP10], [AKAP10; AKAP10; PRKA10; AKAP-10; D-AKAP2; D-AKAP-2; AKAP-10; D-AKAP-2; PRKA10] |
Gene, Accession # | [AKAP10], Gene ID: 11216, NCBI: NP_009133.2, UniProt: O43572 |
Catalog # | MBS1492091 |
Price | $120, $160 |
Order / More Info | Human AKAP10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |