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Antigenic Specificity | Cry1 (C-term), 556-586 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Cry1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-586 amino acids from the C-terminal region of human Cry1. Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central ?gears?driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function v |
Immunogen | n/a |
Other Names | [Cryptochrome-1; CRY1; PHLL1] |
Gene, Accession # | [CRY1], Gene ID: 1407, NCBI: NP_004066.1, UniProt: Q16526 |
Catalog # | MBS9208683 |
Price | $165, $370 |
Order / More Info | Cry1 (C-term), 556-586 Antibody from MYBIOSOURCE INC. |
Product Specific References | Griffin, E.A. Jr., et al., Science 286(5440):768-771 (1999). van der Horst, G.T., et al., Nature 398(6728):627-630 (1999). Kobayashi, K., et al., Nucleic Acids Res. 26(22):5086-5092 (1998). Hsu, D.S., et al., Biochemistry 35(44):13871-13877 (1996). van der Spek, P.J., et al., Genomics 37(2):177-182 (1996). |